.beta.-lactamase inhibiting 6-(alkoxyamino-...

Details .beta.-lactamase inhibiting 6-(alkoxyamino-... .beta.-lactamase inhibiting 6-(alkoxyamino-...

C - Chemistry, Metallurgy

07

D

260/111, 260/118

C07D 499/04 (2006.01) C07D 499/00 (2006.01)

Patent

CA 1247597

BETA-LACTAMASE INHIBITING 6-(ALKOXYAMINO- METHYL)PENICILLANIC ACID 1,1-DIOXIDE AND DERIVATIVES Abstract 6-alpha/beta-[(C1-C4)Alkoxyaminomethyl and benzyloxyaminomethyl]penicillanic acid 1,1-dioxides, pharmaceutically acceptable salts thereof and con- ventional esters thereof hydrolyzable under physio- logical conditions, all of which are useful in medicine as beta-lastamase inhibitors; intermediates and processes therefor; and a process for the con- version of the present compounds to 6-alpha- and 6- beta-(aminomethyl)penicillanic acid 1,1-dioxides and derivatives.

455812

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