C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/245.1, 260/3
C07D 205/08 (2006.01) C07D 205/085 (2006.01) C07D 403/04 (2006.01) C07D 405/00 (2006.01) C07D 405/04 (2006.01) C07D 405/14 (2006.01)
Patent
CA 1204746
Abstract There are described .beta.-lactams of the general formula Image I in which R1 represents lower 2-alkenyl or 1-alkenyl or a group of the formula -CH2-CH(OR4)2 (a) -CH2-CHO (b) -CO-CH ( OH ) 2 (c) (d) Image -CH=CH-R9 (e) or -CHO (f) wherein R4 signifies lower alkyl, R9 signifies a tertiary lower cyclo- aliphatic or aliphatic amino group and n signifies the number 0 or 1, and wherein further R2 represents amino or a group convertible into amino and R3 represents a lower organic group, with the proviso that when R2 signifies amino R1 represents lower 2-alkenyl or 1-alkenyl or one of the groups (a), (c) and (d), as well as their manufacture. These compounds are useful as intermediates for the manufacture of antimicrobially active .beta.-lactams.
433590
Gowling Lafleur Henderson Llp
Hoffmann-La Roche Limited
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