Beta-lactams and their production

C - Chemistry – Metallurgy – 07 – D

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C07D 205/08 (2006.01) C07D 477/04 (2006.01) C07D 487/04 (2006.01) C07F 7/10 (2006.01) C07F 7/18 (2006.01) C07F 9/572 (2006.01)

Patent

CA 1278295

Abstract: The present invention is directed to beta-lactam compounds of the formula: Image (I) wherein R1 and R2 are the same or different and each represent a hydrogen atom or a lower alkyl group, R3 is a lower alkyl group, R4 is a hydrogen atom, a carboxyl- protecting group or a thiolcarboxyl-protecting group, X is a hydrogen atom, a hydroxyl group or a protected hydroxyl group, Y is an oxygen atom or a sulfur atom and COZ is a carboxyl group, an activated or protected carboxyl group, a thiolcarboxyl group or an activated or protected thiol- carboxyl group. The compounds are useful as intermediates in the stereospecific production of l-alkylcarbapenem compounds.

498692

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