Beta-parvin expression for use in diagnostic methods for...

A - Human Necessities – 61 – K

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A61K 48/00 (2006.01) A61K 31/7088 (2006.01) C12P 21/08 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2482380

The invention is directed to polynucleotides encoding .beta.-parvin, a newly identified tumor suppressor gene the alteration of which is involved ire the occurrence of breast cancer in a patient, as well as to corresponding expressed polypeptides. The invention also concerns diagnostic methods using the .beta.-parvin polynucleotides and/or peptides and embodiments thereof as diagnostic or therapeutic tools for breast cancer or in assays to identify pharmacological agents for the treatment of breast cancer.

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