C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/47 (2006.01) A61K 38/17 (2006.01) A61P 25/28 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2489754
Provided are peptides having Beta-sheet breaking ability, based on the requeme LPFFD, useful in the treatment and prevention of diseases such as Alzheimer's disease, Dementia pugilistica (including head trauma), hereditary Cerebral Haemorrhage with amyloidosis of the Dutch type (HCHWA-D) and vascular dementia with amyloid angiopathy.
L'invention concerne des peptides possédant une capacité de rupture de feuillets .beta. et étant utiles dans le traitement et la prévention de maladies, telles que la maladie d'Alzheimer, la démence pugilistique (notamment un traumatisme crânien), l'hémorragie cérébrale héréditaire avec amylose de type hollandais (HCHWA-D) et la démence vasculaire avec angiopathie amyloïde.
Adessi Celine
Halazy Serge
Rueckle Thomas
Soto-Jara Claudio
Applied Research Systems Ars Holding N.v.
Kirby Eades Gale Baker
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