Beta-substituted beta-aminoethyl phosphonates

C - Chemistry – Metallurgy – 07 – F

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Details

C07F 9/02 (2006.01) C07F 9/38 (2006.01) C07F 9/40 (2006.01) C07F 9/58 (2006.01)

Patent

CA 2426773

The present invention relates to novel .beta.-substituted-.beta.- aminoethylphosphonate derivatives and their uses for lowering plasma levels of apo(a), Lp(a), apo B, apo B associated lipoproteins (low density lipoproteins and very low density lipoproteins) and for lowering plasma levels of total cholesterol.

La présente invention concerne des nouveaux dérivés de .beta.-aminoéthylphosphonate .beta.-substitués ainsi que leurs utilisations pour abaisser les concentrations plasmatiques d'apo(a), de Lp(a), d'apo B et des lipoprotéines associées à apo B (lipoprotéines à faible densité et lipoprotéines à très faible densité), et pour abaisser les concentrations plasmatiques du cholestérol total.

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