Betacellulin muteins

Details Betacellulin muteins Betacellulin muteins

C - Chemistry, Metallurgy

12

N

C12N 15/19 (2006.01) A61K 38/19 (2006.01) C07K 14/475 (2006.01) C07K 14/485 (2006.01) C07K 14/52 (2006.01) C12P 21/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2353909

The betacellulin mutein or its salt of the present invention is useful for better therapeutic drug for diabetes, since they have intact BTC activity and reduced EGF activity, and no antigenicity-related problems.

L'invention concerne une mutéine de bêtacelluline, ou des sels de celle-ci, laquelle exerce une activité réduite EGF tout en soutenant une activité BTC. Etant donné que cette mutéine est dépourvue d'antigénicité, elle constitue un excellent remède utile pour le diabète.

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