Bhlh-pas proteins, genes thereof and utilization of the same

Details Bhlh-pas proteins, genes thereof and utilization of the same Bhlh-pas proteins, genes thereof and utilization of the same

C - Chemistry, Metallurgy

12

N

C12N 15/09 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/12 (2006.01) C12P 21/02 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) G01N 33/566 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2433501

The invention provides any of the proteins (a) to (e): (a) a protein comprising the amino acid sequence represented by any of SEQ ID Nos.1 to 3, (b) a protein comprising an amino acid sequence exhibiting an amino acid identity of 90% or more to the amino acid sequence represented by any of SEQ ID Nos.1 to 3 and also having a transcription regulation ability, (c) a protein comprising an amino acid sequence encoded by a DNA which hybridizes under a stringent condition with a DNA consisting of the nucleotide sequence represented by the nucleotide numbers 102 to 2507 in the nucleotide sequence represented by SEQ ID No.4 and also having a transcription regulation ability, (d) a protein comprising an amino acid sequence encoded by a DNA which hybridizes under a stringent condition with a DNA consisting of the nucleotide sequence represented by the nucleotide numbers 51 to 2456 in the nucleotide sequence represented by SEQ ID No.5 and also having a transcription regulation ability, (e) a protein comprising an amino acid sequence encoded by a DNA which hybridizes under a stringent condition with a DNA consisting of the nucleotide sequence represented by the nucleotide numbers 35 to 2440 in the nucleotide sequence represented by SEQ ID No.6 and also having a transcription regulation ability, or a DNA encoding the same.

L'invention porte sur les protéines a à c suivantes et sur les ADN codant pour elles: (a) protéine représentée par toute séquence d'acides aminés SEQ ID NOS: 1 à 3; (b) protéine représentée par une séquence d'acides aminés identique à 90 % ou plus avec toute séquence SEQ ID NOS: 1 à 3, et présentant une capacité de régulation transcriptionnelle; (c) protéine représentée par une séquence d'acides aminés codée par un ADN et hybridable dans des conditions rigoureuses: à un ADN comprenant la séquence de base représentée par les N· de base 102 à 2507 de la séquence représentée par SEQ ID NOS: 4; à un ADN comprenant la séquence de base représentée par les N· de base 51 à 2456 de la séquence représentée par SEQ ID NOS: 5; ou à un ADN comprenant la séquence de base représentée par les N· de base 35 à 2440 de la séquence représentée par SEQ ID NOS: 6, et présentant une capacité de régulation transcriptionnelle.

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