Bi-aryl meta-pyrimidine inhibitors of kinases

Details Bi-aryl meta-pyrimidine inhibitors of kinases Bi-aryl meta-pyrimidine inhibitors of kinases

C - Chemistry, Metallurgy

07

D

C07D 239/48 (2006.01) A61K 31/505 (2006.01) C07D 239/49 (2006.01) C07D 207/06 (2006.01)

Patent

CA 2628283

The invention provides biaryl meta-pyrimidine compounds having the general structure (A). The pyrimidine compounds of the invention are capable of inhibiting kinases, such as members of the Jak kinase family, and various other specific receptor and non receptor kinases.

La présente invention concerne des dérivés de biaryl-méta-pyrimidine de structure générale (A). Les dérivés de pyrimidine selon l'invention sont capables d'inhiber des kinases, par exemple les membres de la famille de kinases Jak, et diverses autres kinases spécifiques de type récepteur et non récepteur.

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