Biallelic markers for use in constructing a high density...

Details Biallelic markers for use in constructing a high density... Biallelic markers for use in constructing a high density...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2324866

The present invention relates to genomic maps comprising biallelic markers, new biallelic markers, and methods of using biallelic markers. Primers hybridizing to regions flanking these biallelic markers are also provided. This invention provides polynucleotides and methods suitable for genotyping a nucleic acid containing sample for one or more biallelic markers of the invention. Further, the invention provides a number of methods utilizing the biallelic markers of the invention including methods to detect a statistical correlation between a biallelic marker allele and a phenotype and/or between a biallelic marker haplotype and a phenotype.

La présente invention concerne des cartes génomiques comprenant des marqueurs biallèles, des procédés d'utilisation des marqueurs biallèles et des amorces qui s'hybrident aux régions des flancs des marqueurs biallèles. Cette invention concerne les nucléotides et les procédés qui conviennent au génotypage d'un échantillon contenant un acide nucléique pour un ou plusieurs marqueurs biallèles de l'invention. L'invention concerne aussi un nombre de méthodes qui utilisent les marqueurs biallèles de l'invention y compris des méthodes de détection d'une corrélation statistique entre un marqueur biallèle et un phénotype et/ou entre un haplotype de marqueur biallèle et un phénotype.

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