Biallelic markers of d-amino acid oxidase and uses thereof

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01)

Patent

CA 2469923

The invention concerns the human DAO gene, polynucleotides, and biallelic markers. The invention also concerns the association established between schizophrenia and the biallelic markers. The invention provides means to determine the predisposition of individuals to schizophrenia or related CNS disorder, as well as means for the disease diagnosis and prognosis.

L'invention concerne le gène de diamine oxydase (DAO) humain, des polynucléotides, et des marqueurs bialléliques. L'invention concerne également l'association établie entre la schizophrénie et les marqueurs bialléliques. L'invention concerne des moyens permettant de déterminer la prédisposition des individus à la schizophrénie ou à un trouble en rapport avec le système nerveux central (CNS), ainsi que des moyens destinés au diagnostic et au pronostic.

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