Biaryl and biheteroaryl compounds useful in treating iron...

C - Chemistry – Metallurgy – 07 – C

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C07C 279/20 (2006.01) A61K 31/155 (2006.01) A61K 31/381 (2006.01) A61P 7/00 (2006.01) C07C 279/28 (2006.01) C07C 317/42 (2006.01) C07C 323/43 (2006.01) C07D 333/34 (2006.01)

Patent

CA 2678949

This invention is directed to compounds of formula (I), wherein A, B, m, n, R1, R2 and R3 are as defined herein, as a stereoisomer, enantiomer, tautomer thereof or mixtures thereof; or a pharmaceutically acceptable salt, solvate or prodrug thereof, for the treatment of iron disorders. This invention is also directed to pharmaceutical compositions comprising the compounds and methods of using the compounds to treat iron disorders.

L'invention concerne des composés de formule (I), dans laquelle A, B, m, n, R1, R2 et R3 sont tels que définis dans le présent document, un stéréoisomère, énantiomère, tautomère de ces composés ou des mélanges de ces composés ; ou un sel, un solvate ou un promédicament pharmaceutiquement acceptable de ces composés, pour le traitement des troubles du fer. L'invention concerne également des compositions pharmaceutiques qui comprennent les composés et des procédés d'utilisation des composés pour traiter les troubles du fer.

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