C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 207/16 (2006.01) A61K 31/4439 (2006.01) A61P 9/10 (2006.01) C07D 213/06 (2006.01) C07D 213/64 (2006.01) C07D 213/74 (2006.01) C07D 213/75 (2006.01) C07D 213/79 (2006.01) C07D 213/84 (2006.01) C07D 213/89 (2006.01) C07D 231/12 (2006.01) C07D 233/90 (2006.01) C07D 239/42 (2006.01) C07D 275/06 (2006.01) C07D 285/135 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01) C07D 403/04 (2006.01) C07D 471/04 (2006.01) C07D 473/18 (2006.01) C07D 473/40 (2006.01)
Patent
CA 2722582
The present invention relates to a genus of biaryl compounds containing at least one further ring. The compounds are PDE4 inhibitors useful for the treatment and prevention of stroke, myocardial infarct and cardiovascular inflammatory diseases and disorders. The compounds have general formula I: (formula should be inserted here). A particular embodiment is (a second formula should be inserted here)
La présente invention concerne un genre de composés biaryle contenant au moins un cycle supplémentaire. Les composés sont des inhibiteurs de PDE4 utiles pour le traitement et la prévention d'un accident vasculaire cérébral, d'un infarctus du myocarde et de maladies et troubles inflammatoires cardiovasculaires. Les composés répondent à la formule générale I : (la formule doit être insérée ici). Un mode de réalisation particulier est (une seconde formule doit être insérée ici).
Burgin Alex
Gurney Mark E.
Hagen Timothy
Hategan Georgeta
Kiselyov Alexander
Cassan Maclean
Decode Genetics Ehf.
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