C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 207/16 (2006.01) C07D 213/06 (2006.01) C07D 213/64 (2006.01) C07D 213/74 (2006.01) C07D 213/75 (2006.01) C07D 213/79 (2006.01) C07D 213/84 (2006.01) C07D 231/12 (2006.01) C07D 239/42 (2006.01) C07D 285/135 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01) C07D 471/04 (2006.01) C07D 473/18 (2006.01) C07D 473/40 (2006.01)
Patent
CA 2722611
The present invention relates to a genus of biaryl compounds containing at least one further ring. The compounds are PDE4 inhibitors useful for the treatment and prevention of stroke, myocardial infarct and cardiovascular inflammatory diseases and disorders. The compounds have general formula Ia, Ib, Ic or Id: (Ia) (Ib) (Ic) (Id). A particular embodiment is (I).
La présente invention concerne un genre de composés de biaryle qui contiennent au moins un autre noyau. Les composés sont des inhibiteurs de la PDE4 utiles pour le traitement et la prévention d'un accident vasculaire cérébral, d'un infarctus du myocarde et de maladies et troubles d'inflammation cardiovasculaire. Les composés sont représentés par la formule générale Ia, Ib, Ic ou Id : (Ia) (Ib) (Ic) (Id). Un mode de réalisation particulier est (I).
Burgin Alex
Gurney Mark
Hagen Timothy
Kiselyov Alexander
Rao Munagala
Cassan Maclean
Decode Genetics Ehf
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