Biaryl substituted diazabicycloalkane derivatives

Details Biaryl substituted diazabicycloalkane derivatives Biaryl substituted diazabicycloalkane derivatives

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/407 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2705011

The invention relates biaryl substituted diazabicycloalkanes of foraula (I), and more particularly bicycloheteroaryl substituted fused diazabicycloalkane derivatives, compositions comprising such compounds, and such compounds for use for treat- ing or preventing conditions and disorders related to both <x7 and a4.beta.2 nAChR activity Formula: (I).

L'invention concerne des diazabicycloalcanes à substitution biaryle représentés par la formule (I), et plus particulièrement des dérivés de diazabicycloalcanes à substitution bicyclohétéroaryle fusionnés, des compositions contenant de tels composés, et de tels composés en vue d'une utilisation pour traiter ou prévenir des pathologies et des troubles liés à l'activité du récepteur nicotinique de l'acétylcholine (nAChR) tant de type a7 que de type a4ß2. Formule : (I).

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