Biaryl substituted nitrogen containing heterocycle...

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 207/12 (2006.01) A61K 31/40 (2006.01) A61K 31/435 (2006.01) A61P 29/00 (2006.01) C07D 211/46 (2006.01)

Patent

CA 2634701

The present invention relates to a chemical genus of biaryl substituted nitrogen-attached heterocycles that are inhibitors of LTA4H (leukotriene A4 hydrolase). The compounds have the formula (I). They are useful for the treatment and prevention and prophylaxis of inflammatory diseases and disorders.

La présente invention concerne une espèce chimique d'hétérocycles à substitution biaryl, liés à de l'azote, lesdits hétérocycles étant des inhibiteurs de LTA4H (leucotriène A4 hydrolase). Les composés selon l'invention sont représentés par la formule (I) et servent au traitement, à la prévention et à la prophylaxie de maladies et états inflammatoires.

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