Biaryl urea and related compounds

Details Biaryl urea and related compounds Biaryl urea and related compounds

C - Chemistry, Metallurgy

07

D

C07D 213/75 (2006.01) A61K 31/275 (2006.01) A61K 31/395 (2006.01) A61K 31/66 (2006.01) C07C 275/40 (2006.01) C07C 275/42 (2006.01) C07C 279/08 (2006.01) C07C 279/28 (2006.01) C07C 335/22 (2006.01) C07D 209/08 (2006.01) C07D 209/44 (2006.01) C07D 239/42 (2006.01) C07D 241/20 (2006.01) C07F 9/40 (2006.01) C07F 9/547 (2006.01)

Patent

CA 2132771

Abstract BIARYL UREA AND RELATED COMPOUNDS Compounds having the formula I Image and pharmaceutically acceptable salts thereof wherein X is a single bond, O, CO, S, NH or N(lower alkyl); Y is O, S or NCN; and R1 to R5 are as defined herein. These compounds have potassium channel activating activity and are useful, therefore for example, as cardiovascular agents.

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