Biazacyclic crf antagonists

Details Biazacyclic crf antagonists Biazacyclic crf antagonists

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/505 (2006.01) A61K 31/53 (2006.01) C07D 235/08 (2006.01) C07D 471/04 (2006.01) C07D 473/00 (2006.01)

Patent

CA 2281525

CRF receptor antagonists are disclosed which have utility in the treatment of a variety of disorders, including the treatment of disorders manifesting hypersecretion of CRF in a warm-blooded animal, such as stroke. In formulae (I), (II), (III), (IV), (V) and (VI), A, B, C are all C or N. Ar, R1 and R2 are as defined in the application.

L'invention concerne des antagonistes de récepteurs du CRF, utiles dans le traitement de diverses affections, notamment dans le traitement d'affections dans lesquelles on observe une hypersécrétion de CRF chez des animaux à sang chaud, telles que des accidents vasculaires cérébraux.

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