Bicyclic [3.1.0] derivatives as glycine transporter inhibitors

Details Bicyclic [3.1.0] derivatives as glycine transporter inhibitors Bicyclic [3.1.0] derivatives as glycine transporter inhibitors

C - Chemistry, Metallurgy

07

D

C07D 413/14 (2006.01) A61K 31/5377 (2006.01)

Patent

CA 2542279

The present invention relates to a series of substituted bicyclic [3.1.0]amines of the Formula I: Wherein A, B, D, Q, V, W, X, Y, Z, R2, R3, R4, R5, R14, R15, R30.o, p, s, t and q are as defined in the specification, their pharmaceutically acceptable salts, pharmaceutical compositions thereof, and their use for the enhancement of cognition and the treatment of the positive and negative symptoms of schizophrenia and other psychoses in mammals, including humans.

L'invention concerne une série d'amines [3.1.0] bicycliques substituées de formule (I), dans laquelle A, B, D, Q, V, W, X, Y, Z, R?2¿, R?3¿, R?4¿, R?5¿, R?14¿, R?15¿, R?30¿, o, p, s, t et q ont la signification indiquée dans la description, leurs sels pharmaceutiquement acceptables, des compositions pharmaceutiques contenant lesdits composés, et l'utilisation de ces compositions pour améliorer les facultés cognitives et traiter les symptômes positifs et négatifs de la schizophrénie et d'autres psychoses chez des mammifères, par exemple chez les êtres humains.

Affiliated with

Also associated with

Rating

Bicyclic [3.1.0] derivatives as glycine transporter inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Bicyclic [3.1.0] derivatives as glycine transporter inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Bicyclic [3.1.0] derivatives as glycine transporter inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1784976