Bicyclic amino acids as pharmaceutical agents

Details Bicyclic amino acids as pharmaceutical agents Bicyclic amino acids as pharmaceutical agents

C - Chemistry, Metallurgy

07

C

C07C 229/28 (2006.01) A61K 31/195 (2006.01)

Patent

CA 2386297

The compounds of the instant invention are bicyclic amino acids useful in the treatment of epilepsy, faintness attacks, hypokinesia, cranial disorders, neurodegenerative disorders, depression, anxiety, panic, pain, arthritis, neuropathological disorders, and sleep disorders. Processes for the preparation of the final products and intermediates useful in the process are included. Pharmaceutical compositions containing one or more of the compounds are also included. (see formula I), (see formula II), (see formula III) or (see formula IV)

Les composés de la présente invention sont des acides aminés bicycliques utiles dans le traitement de l'épilepsie, d'évanouissements, d'hypocinésie, de maux de tête, de maladies neurodégénératives, de la dépression, de l'anxiété, de peurs paniques, de douleurs, de l'arthrite, de troubles neuropathologiques et de troubles du sommeil. L'invention concerne également des procédés de préparation de ces composés et des intermédiaires de cette préparation. L'invention porte, enfin, sur les compositions pharmaceutiques contenant un ou plusieurs de ces composés.

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