C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 495/04 (2006.01) A61K 31/4196 (2006.01) A61P 19/00 (2006.01) C07D 249/14 (2006.01) C07D 401/04 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 403/14 (2006.01) C07D 409/14 (2006.01) C07D 417/14 (2006.01)
Patent
CA 2710043
Bicyclic aryl substituted triazoles or heteroaryl substituted triazoles and pharmaceutical compositions containing the compounds are disclosed as being useful in inhibiting the activity of the receptor protein tyrosine kinase Ax1. Methods of using the compounds in treating diseases or conditions associated with Ax1 activity are also disclosed.
La présente invention concerne des triazoles à substitution aryle bicycliques ou des triazoles à substitution hétéroaryle bicycliques ainsi que des compositions pharmaceutiques contenant les composés utiles pour inhiber l'activité de la protéine kinase réceptrice Axl. L'invention concerne également des procédés d'utilisation des composés dans le traitement de maladies ou d'états associés à l'activité d'Axl.
Ding Pingyu
Goff Dane
Heckrodt Thilo
Holland Sacha
Litvak Joane
Gowling Lafleur Henderson Llp
Rigel Pharmaceuticals Inc.
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