Bicyclic chiral compounds

C - Chemistry – Metallurgy – 07 – D

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C07D 265/12 (2006.01) C07C 51/64 (2006.01) C07C 57/64 (2006.01) C07C 209/88 (2006.01) C07C 211/27 (2006.01) C07C 247/20 (2006.01) C07C 271/32 (2006.01) C07C 309/73 (2006.01) C07C 311/25 (2006.01) C07C 317/18 (2006.01) C07D 263/52 (2006.01)

Patent

CA 2064217

2064217 9118890 PCTABS00008 A compound of general formula I(a) and/or I(b) and/or I(c), in which R1 represents a methyl group or a group of the general formula -CH2.SO2.R2 or -CH2.SO2.NR2R3, in which each of R2 and R3 independently represents an alkyl, cycloalkyl or optionally substituted phenyl or phenalkyl group; each of R4, R5 and R6 independently represents a hydrogen atom or a methyl group; X represents a group of formula C(CH3)2 or, when both of R5 and R6 represent methyl groups, also represents a group of formula CH2; Q represents an oxygen or sulphur atom; and Y represents a hydrogen atom, an alkali metal atom or a group of the general formula -COA in which A represents a halogen atom or an alkyl or alkoxy group optionally substituted by a phenyl, cycloalkyl, alkoxy or alkylcarbonyl group. The compounds are bicyclic optically active compounds and are useful in the synthesis of optical isomers and separation of optical isomers from mixtures.

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