Bicyclic compounds, their production and use

C - Chemistry – Metallurgy – 07 – K

Patent

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530/5.06, 260/35

C07K 5/00 (2006.01) A61K 31/48 (2006.01) A61K 39/00 (2006.01)

Patent

CA 1287446

ABSTRACT OF THE DISCLOSURE New bicyclic compounds of the formula: (II') Image wherein R1 and R2 are the same or different and each represents hydrogen, hydroxyl or lower alkoxy R3 is hydrogen or lower alkyl, R4 is hydrogen, lower alkyl amino-lower-alkyl or acylamino-lower-alkyl, R7 is hydrogen or benzyloxycarbonyl, and m and n are each 1 or 2, or salts thereof are disclosed. The compounds (II) are useful for producing derivatives which exhibit inhibitory activity of angiotensin converting enzyme and bradykinin decomposing enzyme.

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