C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
530/5.06, 260/35
C07K 5/00 (2006.01) A61K 31/48 (2006.01) A61K 39/00 (2006.01)
Patent
CA 1287446
ABSTRACT OF THE DISCLOSURE New bicyclic compounds of the formula: (II') Image wherein R1 and R2 are the same or different and each represents hydrogen, hydroxyl or lower alkoxy R3 is hydrogen or lower alkyl, R4 is hydrogen, lower alkyl amino-lower-alkyl or acylamino-lower-alkyl, R7 is hydrogen or benzyloxycarbonyl, and m and n are each 1 or 2, or salts thereof are disclosed. The compounds (II) are useful for producing derivatives which exhibit inhibitory activity of angiotensin converting enzyme and bradykinin decomposing enzyme.
468185
Miyake Akio
Nishikawa Kohei
Oka Yoshikazu
Fetherstonhaugh & Co.
Miyake Akio
Nishikawa Kohei
Oka Yoshikazu
Takeda Chemical Industries Ltd.
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