Bicyclic derivatives for use in the treatment of androgen...

Details Bicyclic derivatives for use in the treatment of androgen... Bicyclic derivatives for use in the treatment of androgen...

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/4196 (2006.01) A61K 31/437 (2006.01) A61K 31/5025 (2006.01) A61P 35/00 (2006.01) C07D 487/04 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2709514

The invention concerns bicyclic compounds of Formula (I), wherein the integers X1, X2, X3, Ring A, R4, R5 and m are as defined in the description. The present invention also relates to processes for the preparation of such compounds, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use in the prevention or treatment of androgen-receptor associated conditions.

L'invention porte sur des composés bicycliques représentés par la Formule (I), dans laquelle les entiers X1, X2, X3, le noyau A, R4, R5 et m sont tels que définis dans la description. La présente invention porte également sur des procédés de préparation de ces composés, sur des compositions pharmaceutiques les contenant et sur leur utilisation dans la fabrication d'un médicament destiné à être utilisé dans la prévention ou le traitement d'affections associées au récepteur des androgènes.

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