C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
167/228, 260/281
C07F 9/576 (2006.01) A61K 31/675 (2006.01)
Patent
CA 1321793
NOVEL BICYCLIC DIPHOSPHONATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM ABSTRACT OF THE DISCLOSURE The present invention relates to novel compounds having nitrogen-containing, saturated bicyclic cylopentane-fused rings which are geminally disubstituted with phosphonate groups. Most preferred compounds of the present invention have the general structure: Image The present invention further relates to pharmaceutical compositions containing these novel compounds. Finally, this invention relates to methods for treating or preventing diseases characterized by abnormal calcium and phosphate metabolism by utilizing a compound or pharmaceutical composition of the present invention.
554628
Buckingham Kent Warren
Ebetino Frank Hallock
Mcosker Jocelyn Elaine
Buckingham Kent Warren
Ebetino Frank Hallock
Kirby Eades Gale Baker
Mcosker Jocelyn Elaine
Procter & Gamble Pharmaceuticals Inc.
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