Bicyclic heteroaromatic compounds as kinase inhibitors

Details Bicyclic heteroaromatic compounds as kinase inhibitors Bicyclic heteroaromatic compounds as kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 495/04 (2006.01) A61K 31/4365 (2006.01) A61P 19/02 (2006.01) A61P 29/00 (2006.01) A61P 37/02 (2006.01)

Patent

CA 2495518

A series of 5-6 fused ring bicyclic heteroaromatic derivatives, based in particular on the 6-oxo-6,7-dihydrothieno[2,3-b]pyridine ring system, being inhibitors of p38 kinase, are accordingly of use in medicine, for example in the treatment and/or prevention of immune or inflammatory disorders.

L'invention a trait à une série de dérivés hétéroaromatiques bicycliques à 5-6 cycles fusionnés, basés en particulier sur le système cyclique de 6-oxo-6,7-dihydrothiéno[2,3-b]pyridine, qui sont des inhibiteurs de la kinase p38. Les dérivés selon l'invention sont d'utilité dans le domaine de la médecine, par exemple pour le traitement et/ou la prévention de troubles immunitaires ou inflammatoires.

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