C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 239/94 (2006.01) A61K 31/517 (2006.01) A61P 1/00 (2006.01) A61P 11/00 (2006.01) A61P 35/00 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01)
Patent
CA 2631813
The invention relates to bicyclic heterocycles of general formula (I), the tautomers thereof, the mixtures and salts thereof, especially the physiologically acceptable salts thereof comprising inorganic or organic acids, which have valuable pharmaceutical properties, particularly an inhibitive effect on signal transduction mediated by tyrosine kinases, the use thereof for treating diseases, especially tumor diseases and benign prostatic hyperplasia (BPH), lung diseases, and respiratory tract diseases, and the production thereof.
L'invention concerne des hétérocycles bicycliques représentés par la formule (I), leurs tautomères, stéréoisomères, mélanges et sels, notamment leurs sels physiologiquement compatibles, contenant des acides anorganiques ou organiques, présentant des propriétés pharmaceutiques intéressantes, notamment un effet inhibiteur sur la transduction de signal provoquée par des tyrosine kinases. L'invention concerne également l'utilisation de ces composés pour le traitement de maladies, notamment de maladies tumorales, de l'hyperplasie prostatique bénigne (BPH), de maladies pulmonaires et de maladies des voies respiratoires, ainsi que leur fabrication.
Himmelsbach Frank
Jung Birgit
Santagostino Marco
Soyka Rainer
Boehringer Ingelheim International Gmbh
Fetherstonhaugh & Co.
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