C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 405/14 (2006.01) A61K 31/517 (2006.01) A61K 31/5377 (2006.01) A61P 35/00 (2006.01) C07D 413/14 (2006.01)
Patent
CA 2403152
The invention relates to bicyclic heterocycles of the general formula (I), wherein R a to R d, A to C and X are defined as in claims 1 to 5. The invention further relates to the tautomers, stereoisomers and salts thereof, especially the physiologically salts with inorganic or organic acids or bases thereof, having valuable pharmacological properties, especially an inhibitory effect on tyrosine kinase mediated signal transduction. The invention further relates to the use of said compounds for treating diseases, especially tumor diseases, diseases of the lungs and the respiratory tract, and to the production of said compounds.
La présente invention concerne des hétérocycles bicycliques de la formule générale (I), dans laquelle Ra à Rd, A à C et X correspondent aux définitions données dans les revendications 1 à 5, leurs tautomères, leurs stéréoisomères et leurs sels, en particulier leurs sels physiologiquement tolérés avec des acides ou des bases inorganiques ou organiques, lesquels présentent des caractéristiques pharmacologiques appréciables, en particulier un effet inhibiteur sur la transduction de signal induite par les tyrosine kinases. L'invention concerne également l'utilisation de ces composés pour le traitement de maladies, en particulier de maladies tumorales, de maladies des poumons et des voies respiratoires, ainsi que la production de ces composés.
Blech Stefan
Himmelsbach Frank
Jung Birgit
Langkopf Elke
Solca Flavio
Boehringer Ingelheim Pharma Gmbh & Co. Kg
Boehringer Ingelheim Pharma Kg
Fetherstonhaugh & Co.
LandOfFree
Bicyclic heterocycles, pharmaceutical compositions... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Bicyclic heterocycles, pharmaceutical compositions..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Bicyclic heterocycles, pharmaceutical compositions... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2050307