A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/40 (2006.01) A61K 31/415 (2006.01) A61K 31/495 (2006.01) C07D 209/44 (2006.01) C07D 231/56 (2006.01) C07D 237/26 (2006.01)
Patent
CA 2545659
Disclosed are compounds of the Formula (I) and pharmaceutically acceptable salts and prodrugs thereof, wherein R1, R2, R7, R8, R9, R10, R20, R21,and R22 are as defined in the specification. Such compounds are MFK inhibitors and useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals, and inflammatory conditions. Also disclosed are methods of using such compounds in the treatment of hyperproliferative diseases in mammals and pharmaceutical compositions containing such compounds.
L'invention concerne des composés de la formule (I) et leurs sels pharmaceutiquement acceptables et pro-médicaments, R?1¿, R?2¿, R?7¿, R?8¿,? ¿R?9¿, R?10¿, R?20¿,?¿R?21¿ et R?22¿ayant la définition donnée dans la description. De tels composés sont des inhibiteurs de MFK et sont utiles dans le traitement de maladies hyperproliférantes, telles que le cancer et les inflammations, chez les mammifères, et les états inflammatoires. L'invention concerne également des procédés d'utilisation de ces composés dans le traitement des maladies hyperproliférantes chez les mammifères et les compositions pharmaceutiques contenant de tels composés.
Lyssikatos Joseph P.
Wallace Eli
Yang Hong Woon
Array Biopharma Inc.
Gowling Lafleur Henderson Llp
LandOfFree
Bicyclic inhibitors of mek and methods of use thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Bicyclic inhibitors of mek and methods of use thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Bicyclic inhibitors of mek and methods of use thereof will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1857916