Bicyclic pyridine and pyrimidine p38 kinase inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 495/04 (2006.01) A61K 31/519 (2006.01) A61P 19/02 (2006.01) C07D 487/04 (2006.01) C07D 491/04 (2006.01)

Patent

CA 2477721

The present invention discloses compounds corresponding to formula (I), wherein A, R, X, Y, R, R1 and R2 are as defined, pharmaceutical formulations, methods of making and uses thereof in the treatment of p38 kinase mediated diseases.

L'invention porte sur des composés de formule (I) dans laquelle: A, R, X, Y, R, R?1¿ et R?2¿ sont tels que définis dans la description, sur des préparations pharmaceutiques les contenant, et sur leurs procédés de fabrication, et d'utilisation dans le traitement de maladies médiées par la p38 kinase.

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