C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61K 31/5377 (2006.01) C07D 413/12 (2006.01) C07D 487/14 (2006.01) C07D 213/61 (2006.01) C07D 231/38 (2006.01) C07D 231/44 (2006.01) C07D 249/12 (2006.01) C07D 249/14 (2006.01) C07D 255/04 (2006.01)
Patent
CA 2593264
The present invention is directed to novel substituted bicyclic pyrimidines which are inhibitors of the dipeptidyl peptidase-IV enzyme ("DPP-IV inhibitors") and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
La présente invention concerne des nouvelles pyrimidines bicycliques substituées qui constituent des inhibiteurs de l'enzyme de la dipeptidyl-peptidase-IV ("inhibiteurs DPP-IV") et qui sont utilisées dans le traitement ou la prévention de maladies, dans lesquelles est impliquée ladite enzyme, telles que des diabètes et, notamment, des diabète de type 2. Cette invention a aussi pour objet des compositions pharmaceutiques renfermant ces composés et l'utilisation desdits composés et compositions dans la prévention ou le traitement de ces maladies, dans lesquelles est impliquée l'enzyme de la dipeptidyl-peptidase-IV.
Ashton Wallace T.
Caldwell Charles G.
Dong Hong
Gao Ying-Duo
Scapin Giovanna
Gowling Lafleur Henderson Llp
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
LandOfFree
Bicyclic pyrimidines as dipeptidyl peptidase-iv inhibitors... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Bicyclic pyrimidines as dipeptidyl peptidase-iv inhibitors..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Bicyclic pyrimidines as dipeptidyl peptidase-iv inhibitors... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1998921