Bicyclic pyrrolyl amides as glycogen phosphorylase inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 495/04 (2006.01) A61K 31/395 (2006.01) A61K 31/407 (2006.01) A61K 31/427 (2006.01) A61K 31/454 (2006.01) A61K 31/5377 (2006.01) A61K 31/695 (2006.01) C07D 209/52 (2006.01) C07D 487/04 (2006.01) C07D 491/04 (2006.01) C07D 491/048 (2006.01) C07D 495/14 (2006.01) C07D 519/00 (2006.01) C07F 7/10 (2006.01)

Patent

CA 2321379

This invention relates to compounds of Formula I Image or stereoisomers, pharmaceutically acceptable salts or prodrugs thereof or a pharmaceutically acceptable salts of the prodrugs. This invention also relates to pharmaceutical compositions comprising a compound of Formula I, and to methods of treatment of diabetes, insulin resistance, diabetic neuropathy, diabetic nephropathy, diabetic retinopathy, cataracts, hyperglycemia, hypercholesterolemia, hypertension, hyperinsulinemia, hyperlipidemia, atherosclerosis, or tissue ischemia.

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