Bicyclic sphingosine 1-phosphate analogs

Details Bicyclic sphingosine 1-phosphate analogs Bicyclic sphingosine 1-phosphate analogs

C - Chemistry, Metallurgy

07

F

C07F 9/09 (2006.01) A61K 31/133 (2006.01) A61K 31/381 (2006.01) A61K 31/4245 (2006.01) A61K 31/661 (2006.01) A61P 19/00 (2006.01) C07C 215/08 (2006.01) C07C 215/10 (2006.01) C07D 271/06 (2006.01) C07D 333/16 (2006.01) C07D 413/04 (2006.01)

Patent

CA 2696488

Compounds that have agonist activity at one or more of the S1P receptors are provided. The compounds are sphingosine analogs that, after phosphorylation, can behave as agonists at S1P receptors. Formula (I):

L'invention concerne des composés qui ont une activité agoniste au niveau d'un ou plusieurs des récepteurs S1P. Les composés sont des analogues de sphingosine qui, après phosphorylation, peuvent se comporter comme des agonistes au niveau des récepteurs S1P. Formula (I):

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