Bicyclic spla2 inhibitors

Details Bicyclic spla2 inhibitors Bicyclic spla2 inhibitors

A - Human Necessities

61

K

A61K 31/505 (2006.01) A61K 31/535 (2006.01) A61K 31/675 (2006.01) C07D 413/12 (2006.01) C07D 487/04 (2006.01) C07F 9/02 (2006.01) C07F 9/6561 (2006.01)

Patent

CA 2335448

A class of novel pyrrolo[2,3-d]pyrimidine compounds is disclosed together with the use of such compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of diseases such as septic shock.

La présente invention concerne une classe de composés pyrrolo[2,3-d]pyrimidiniques. L'invention concerne également le blocage d'acides gras dont la libération résulte d'une médiation par les sPLA¿2?, ce blocage permettant le traitement d'affections telles que le choc septique.

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