C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/06 (2006.01) A61K 31/505 (2006.01) C07D 401/06 (2006.01) C07D 471/04 (2006.01) C07D 473/04 (2006.01) C07D 475/02 (2006.01) C07D 487/04 (2006.01) C07D 491/04 (2006.01) C07D 495/04 (2006.01) C07D 498/04 (2006.01)
Patent
CA 2210966
The present invention relates to a compound of formula (I) and the pharmaceutically acceptable salts thereof wherein W is a bicyclic heterocyclic ring system. The compounds are .alpha.-1 adrenergic antagonists and are useful in the treatment of BPH; also disclosed are .alpha.-1 antagonist compositions and a method for antagonizing .alpha.-1 receptors and treating BPH.
La présente invention concerne un composé de formule (I) ainsi que ses sels pharmaceutiquement acceptables, W étant un noyau hétérocyclique bicyclique. Les composés sont des antagonistes .alpha.-1 adrénergiques et ils sont utiles dans le traitement de l'hyperplasie prostatique bénigne. L'invention concerne aussi des compositions antagonistes .alpha.-1 adrénergiques et un procédé servant à rendre antagonistes des récepteurs .alpha.-1 et à traiter l'hyperplasie prostatique bénigne.
Altenbach Robert J.
Basha Fatima Z.
Carroll William A.
Drizin Irene
Kerwin James F. Jr.
Abbott Laboratories
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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