Bicyclic tetrahydroxypyrrolizidine

Details Bicyclic tetrahydroxypyrrolizidine Bicyclic tetrahydroxypyrrolizidine

C - Chemistry, Metallurgy

07

D

167/233, 260/299

C07D 487/04 (2006.01) A61K 31/40 (2006.01) C07D 491/22 (2006.01) C07F 7/18 (2006.01)

Patent

CA 2024841

07-27(695)A BICYCLIC TETRAHYDROXYLPYRROLIZIDINE Abstract of the Disclosure Novel bicyclic tetrahydroxylated pyrrolizidines are disclosed which are inhibitors of glycosidase enzymes. A preferred inhibitor is (1lS,2R,6R,7S)-1,2,6- 7-tetrahydroxypyrrolizidine. It is synthesized from D- alycero-talo-heptono-1,4-lactone.

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