Bicycloalkyl derivatives of prostaglandins

C - Chemistry – Metallurgy – 07 – C

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260/235.01, 260/

C07C 69/74 (2006.01) C07C 177/00 (1980.01)

Patent

CA 1112240

ABSTRACT OF THE DISCLOSURE NoYel bicycloalkyl analogues or derivatives of prosta- glandin A, E and F are useful modifiers of smooth muscle activity. The compounds have valuable pharmacological properties as platelet antiaggregating agents and gastric antisecretory agents. The compounds are also valuable pharmscological agents for increasing femoral blood flow and decreasing blood pressure and heart rate.

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