C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
167/208, 167/268
C07C 323/41 (2006.01) C07D 295/18 (2006.01) C07D 295/185 (2006.01) C07D 453/02 (2006.01)
Patent
CA 1332057
ABSTRACT The compounds of this invention are bicyclic, tricyclic, azabicyclic and azatricyclic amides represented by the formula: Image wherein: R1 and R2 are the same or different members of the group consisting of halo, phenyl, substituted phenyl and a Image group wherein n, m and p are independently an integer of from 1 to 8 provided that n + m + p is equal to or less than 10; X is thio, sulfinyl or sulfonyl; Alk is straight or branched chain lower alkylene; R3 is selected from the group consisting of a bicycloalkylamino, tricycloalkylamino, azabicycloalkyl, azatricycloalkyl, azabicycloalkylamino, azatricycloalkylamino or dicycloalkylamino. The compounds are useful as anti-inflammatory and anti-allergy agents.
500837
Deason James Ronald
Mueller Richard August
Partis Richard Allen
G.d. Searle & Co.
Osler Hoskin & Harcourt Llp
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