Bicycloheteroaryl compounds as p2x7 modulators and uses thereof

C - Chemistry – Metallurgy – 07 – D

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C07D 217/24 (2006.01) A61K 31/472 (2006.01) C07D 401/06 (2006.01)

Patent

CA 2680275

Compounds are disclosed that have a formula represented by the following fomula (I). The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.

Cette invention se rapporte à des composés représentés par la formule suivante (I). Lesdits composés peuvent être préparés sous forme de compositions pharmaceutiques, et peuvent être utilisés dans la prévention et le traitement de différentes affections touchant les mammifères, y compris l'homme, et comprenant, notamment, la douleur, l'inflammation et les blessures traumatiques.

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