Bicycloheteroaryl compounds as p2x7 modulators and uses thereof

Details Bicycloheteroaryl compounds as p2x7 modulators and uses thereof Bicycloheteroaryl compounds as p2x7 modulators and uses thereof

C - Chemistry, Metallurgy

07

D

C07D 217/24 (2006.01) A61K 31/472 (2006.01) A61P 25/00 (2006.01) A61P 29/00 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2645556

Bicycloheteroaryl compounds are disclosed that have a formula represented by the following: formula (I). The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.

La présente invention concerne des composés de bicyclohétéroaryle de formule (I). Ces composés peuvent être préparés sous la forme de compositions pharmaceutiques et peuvent être utilisés pour prévenir et traiter chez des mammifères, y compris chez l'homme, un certain nombre d'états pathologiques comprenant, entre autres, la douleur, l'inflammation, les blessures traumatiques, etc.

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