Bicyclononene derivatives as renin inhibitors

Details Bicyclononene derivatives as renin inhibitors Bicyclononene derivatives as renin inhibitors

C - Chemistry, Metallurgy

07

D

C07D 471/08 (2006.01) A61K 31/4995 (2006.01) A61P 9/12 (2006.01) A61P 13/12 (2006.01)

Patent

CA 2577084

The invention relates to novel bicyclononene derivatives of Formula (I); and the use thereof as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors of renin.

La présente invention a pour objet des dérivés originaux du bicyclononène, de Formule (I), ainsi que l~emploi desdits dérivés en tant que composants actifs entrant dans la formulation de préparations pharmaceutiques. La présente invention a également pour objet des éléments afférents auxdits dérivés tels que des procédés de synthèse desdits dérivés, des préparations pharmaceutiques incluant un ou plusieurs desdits dérivés, et plus particulièrement l'utilisation desdits dérivés en tant qu~inhibiteurs de la rénine.

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