Bidirectional promoter from z. mais

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/82 (2006.01) C07K 14/415 (2006.01)

Patent

CA 2744310

The present invention is concerned with the provision of means and methods for gene expression. Specifically, it relates to a polynucleotide comprising an expression control sequence which allows for bidirectional expression of two nucleic acid of interest being operatively linked thereto in opposite orientations. Furthermore, vectors, host cells, non-human transgenic organisms and methods for expressing nucleic acids of interest are provided which are based on the said polynucleotide. Image

Cette invention concerne des moyens et des procédés d'expression génétique. Plus spécifiquement, l'invention concerne un polynucléotide comprenant une séquence de contrôle de l'expression qui permet l'expression bidirectionnelle de deux acides nucléiques d'intérêt qui y sont liés de manière opérationnelle dans des orientations opposées. En outre l'invention décrit des vecteurs, des cellules hôtes, des organismes transgéniques non humains et des procédés permettant l'expression d'acides nucléiques d'intérêt basés sur ledit polynucléotide.

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