Bifunctional antibodies and method of preparing same

Details Bifunctional antibodies and method of preparing same Bifunctional antibodies and method of preparing same

C - Chemistry, Metallurgy

12

N

C12N 15/13 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) C07K 16/46 (2006.01) G01N 33/53 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2097060

2097060 9210209 PCTABS00013 A recombinant antibody capable of binding to two different antigenic sites, contains Fab fragments from the same or, preferably, different antibodies, which are brought into association by complementary interactive domains which have been inserted into a region of the antibody heavy chain constant region.

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