Bifunctional bioadhesive compositions for oral implantology

A - Human Necessities – 61 – K

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A61K 9/00 (2006.01)

Patent

CA 2561728

Bioadhesive solutions of bisphosphonates and Tween 20 are described, with an action that promotes ossification, useful for applications in oral implantology. With respect to the compositions currently in use, these solutions have the advantage of a greater permanence in-situ, before, during and after application of the implant, they present a more intense action of the drug, prolonged over time, and favour complete ossification around the implant.

La présente invention concerne des solutions bioadhésives de bisphosphonates et de Tween dont un effet est de stimuler l'ossification et qui sont utiles pour des applications liées à l'implantologie orale. Par rapport aux compositions actuellement utilisées, ces solutions présentent l'avantage d'une meilleure permanence in situ, avant, pendant et après l'application de l'implant et font preuve d'une action plus intense du médicament, sur une durée prolongée et favorisent l'ossification complète autour de l'implant.

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