Bifunctional fusion molecules for the delivery of antigens...

Details Bifunctional fusion molecules for the delivery of antigens... Bifunctional fusion molecules for the delivery of antigens...

C - Chemistry, Metallurgy

07

K

C07K 19/00 (2006.01) A61K 39/385 (2006.01) A61K 39/395 (2006.01) A61P 37/04 (2006.01) C07K 16/00 (2006.01) C07K 16/08 (2006.01) C07K 16/12 (2006.01) C07K 16/28 (2006.01) C07K 16/46 (2006.01)

Patent

CA 2640416

The invention provides a bifunctional fusion molecule comprising: a first functional domain comprising a first immunoglobulin variable region, a second immunoglobulin variable region and a linker for connecting the first and second variable regions; a second functional domain comprising a moiety for binding to an antigenic agent; wherein the first and second functional domains are linked; and wherein the first functional domain specifically binds to a surface molecule of a professional antigen-presenting cell, and uses thereof.

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