Bifunctional metal chelating conjugates

Details Bifunctional metal chelating conjugates Bifunctional metal chelating conjugates

A - Human Necessities

61

K

A61K 47/48 (2006.01)

Patent

CA 2631784

The present invention is directed to metal chelating conjugates for use as metallopharmaceutical diagnostics or therapeutic agents. Specifically, conjugates of the present invention include a carrier, a metal coordinating moiety, and a urea linkage chemically linking the metal coordinating moiety to the carrier. The carrier is generally utilized for targeting the conjugate to a biological tissue or organ.

L'invention concerne des conjugués chélatant métallifères utilisés en tant que diagnostics métallopharmaceutiques ou agents thérapeutiques. Plus particulièrement, les conjugués de l'invention comprennent un support, un groupe caractéristique de coordination des métaux, et une liaison d'urée liant chimiquement le groupe caractéristique de coordination des métaux au support. Le support est généralement utilisé afin de cibler le conjugué dans un tissu ou un organe biologique.

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