C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 13/00 (2006.01) A61K 51/04 (2006.01) A61K 51/08 (2006.01) A61K 51/10 (2006.01) C07D 213/82 (2006.01) C07D 405/14 (2006.01) C07H 21/00 (2006.01) C07K 1/13 (2006.01) C07K 5/083 (2006.01) C07K 5/103 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 7/14 (2006.01) C07K 7/64 (2006.01) C07K 14/475 (2006.01) C07K 14/575 (2006.01)
Patent
CA 2232340
The invention pertains to novel compounds of general formula (I) in which M stands for a radioisotope of Tc or Re, L stands for a ligand of general formula (II) in which R1, R2, R3, R4, R5 and R6 can have different meanings and stand for groups which are suitable both for the coordinate bonding of metal ions and for coupling to selectively self-concentrating compounds. The novel compounds are used to form complexes of technetium and rhenium and are used in medical diagnostics and therapy.
L'invention concerne de nouveaux composés de formule générale (I), où M représente un radio-isotope de Tc ou Re, et L représente un ligand de formule générale (II) dans laquelle R?1¿, R?2¿, R?3¿, R?4¿, R?5¿ et R?6¿ peuvent avoir différentes significations et représenter des groupes qui sont appropriés pour la liaison de coopération d'ions métalliques et le couplage à des composés à enrichissement sélectif. Ces nouveaux composés servent à la formation de complexes de technétium et de rhénium, et peuvent être utilisés en médecine pour des applications diagnostiques et thérapeutiques.
Dinkelborg Ludger
Hilger Christoph Stephan
Kramp Wolfgang
Platzek Johannes
Raduchel Bernd
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Institut Fur Diagnostikforschung Gmbh An Der Freien Universitat
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