Bifunctional variants of urokinase with improved...

Details Bifunctional variants of urokinase with improved... Bifunctional variants of urokinase with improved...

C - Chemistry, Metallurgy

12

N

C12N 9/72 (2006.01) A61K 38/49 (2006.01) C12N 15/70 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2127897

Abstract Bifunctional urokinase variants possessing improved fibri- nolytic properties and thrombin inhibitory activities, plasmids used in the production of these polypeptides, as well as thrombolytic agents containing one of the bifunc- tional urokinase variants as active ingredient are descri- bed.

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