C - Chemistry – Metallurgy – 08 – L
Patent
C - Chemistry, Metallurgy
08
L
C08L 79/02 (2006.01) A01N 47/44 (2006.01) A01P 1/00 (2006.01) A61L 12/14 (2006.01)
Patent
CA 2667426
A polymeric biguanide composition comprising less than 18 mol% of terminal amine groups as measured by 13C NMR. The polymeric biguanide composition also is characterized by a relative increase in the molar concentration of terminal guanidine groups or terminal cyanoguanidino groups. The invention is also directed to ophthalmic compositions comprising the polymeric biguanide compositions. The polymeric biguanide compositions can be used as an antimicrobial component in an ophthalmic lens care solution, or as a preservative to in a pharmaceutical composition or other health care product.
L'invention concerne une composition de biguanide polymérique comprenant moins de 18 % en moles de groupes amine terminaux, lorsque mesurée par RMN 13C. La composition de biguanide polymérique est également caractérisée par une augmentation relative de la concentration molaire des groupes guanidine terminaux ou groupes cyanoguanidino terminaux. L'invention concerne également des compositions ophtalmiques comprenant les compositions de biguanide polymériques. Les compositions de biguanide polymériques peuvent être utilisées comme un composant antimicrobien dans une solution de soin de lentilles ophtalmiques, ou en tant qu'agent de préservation dans une composition pharmaceutique ou un autre produit de soin sanitaire.
Arch Chemicals Inc.
Bausch & Lomb Incorporated
Ridout & Maybee Llp
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