C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 279/26 (2006.01) A01N 47/44 (2006.01) C07C 323/63 (2006.01) C07D 317/66 (2006.01)
Patent
CA 2064664
The invention presents a biguanide derivative or its salt expressed by a formula: (see formula 1) wherein R represents 3,4-dichlorobenzyl group, 4-chlorophenyl, 3,4-dichlorophenyl group, benzyl group or 4-chlorobenzyl group. wherein R2 represents octyl group, 3,4-dichlorobenzyl group, dodecyl group, decyl group, 3-trifluoromethylphenyl group, 4-bromphenyl group, 4-iodophenyl group, 2,4-dichlorophenyl group, 3,4-dichlorophenyl group, 2,3,4-trichlorophenyl group, 3,4-dimethylphenyl group, 3,4-methylenedioxyphenyl group, 4-t-butylphenyl group 4-ethylthiophenyl group, 1,1,3,3-tetramethylbutyl group, hexyl group, 3-diethylaminopropyl group, (2-diethylamino)-ethyl group, 3-(di-n-butylamino)propyl group, cyclohexylmethyl group, 2,4-dichlorobenzyl group, 4-acetylaminophenyl group, 3,4-methylenedioxybenzyl group, or isobutyl group. (see formula 2) where A represents a lower alkylene group and R3 represents phenyl group which may possess one to three groups selected from a group consisting of halogen atom, lower alkyl group, halogen substituted lower alkyl group and lower alkylthio group as substituent; phenyl lower alkyl group which may posses a halogen atom as substituent on phenyl ring; or alkyl group. This biguanide derivative or its salt is preferably used as the effective amount of a disinfectant for humans, animals, medical appliances, etc.
Higuchi Yukio
Ishikawa Hiroshi
Tamaoka Hisashi
Tsubouchi Hidetsugu
Yasumura Koichi
Otsuka Pharmaceutical Co. Ltd.
Riches Mckenzie & Herbert Llp
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